Adult Soft Tissue Sarcomas
نویسندگان
چکیده
منابع مشابه
Soft Tissue Sarcomas
Soft tissue sarcomas are a heterogeneous group of malignant neoplasms of mesenchymal origin. They account for approximately 1% of all cancer diagnoses and 7% of pediatric malignancies (1,2). Just over half of these patients eventually succumb as a result of the disease. Soft tissue sarcomas typically present as asymptomatic large masses within the retroperitoneum or the proximal lower limbs but...
متن کاملSoft-tissue Sarcomas
This article discusses the epidemiology, diagnosis, and management of primary soft-tissue sarcomas (STS). These musculoskeletal tumors are a rare and heterogeneous group of malignancies, which are best managed by multidisciplinary teams in specialist sarcoma referral centers. Historically, the standard for local control of these tumors has been amputation. Evolutions in multimodality treatment ...
متن کاملComprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas
Sarcomas are a broad family of mesenchymal malignancies exhibiting remarkable histologic diversity. We describe the multi-platform molecular landscape of 206 adult soft tissue sarcomas representing 6 major types. Along with novel insights into the biology of individual sarcoma types, we report three overarching findings: (1) unlike most epithelial malignancies, these sarcomas (excepting synovia...
متن کاملTP53 codon 72 polymorphism in adult soft tissue sarcomas.
Soft tissue sarcomas (STS) are tumors of mesodermal origin, comprising about 1% of all adult neoplasms. Management of such tumors is an important medical challenge. TP53 codon 72 polymorphism results in either the arginine or proline form of the p53 protein; several studies have investigated whether codon 72 polymorphisms are risk and prognostic factors for cancer. We investigated p53 codon 72 ...
متن کاملAdult Head and Neck Soft Tissue Sarcomas: Treatment and Outcome
We have retrospectively analysed the experience of a musculoskeletal oncological unit in the management of adult head and neck soft tissue sarcomas from 1990 to 2005. Thirty-six patients were seen, of whom 24 were treated at this unit, the remainder only receiving advice. The median age of the patients was 46 years. Most of the sarcomas were deep and of high or intermediate grade with a median ...
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ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1987
ISSN: 0003-4932
DOI: 10.1097/00000658-198704000-00003